Intracellular signaling adaptor proteins that contain DEATH EFFECTOR DOMAINS and bind to the cytoplasmic DEATH DOMAIN region found on DEATH DOMAIN RECEPTORS. Many of the proteins in this class take part in intracellular signaling involving TUMOR NECROSIS FACTOR RECEPTORS.

Synonyms: Fas-DISC Components, 0, Death Inducing Signaling Complex Proteins, Death Effector Domain Signaling Adaptor Proteins, Death Effector Domain Containing Proteins, fas Death Inducing Signaling Complex Components, DISC (Death Inducing Signaling Complex), DED Signaling Adaptor Proteins, fas Death-Inducing Signaling Complex Components, Fas DISC Components, Death Domain Receptor Signaling Adaptor Proteins