A negatively-charged extracellular matrix protein that plays a role in the regulation of BONE metabolism and a variety of other biological functions. Cell signaling by osteopontin may occur through a cell adhesion sequence that recognizes INTEGRIN ALPHA-V BETA-3.

A urinary form of osteopontin.

Synonyms: Sialoprotein 1, 0, Bone Sialoprotein I, Sialoprotein 1, Bone, Sialoprotein I, Bone, Osteopontin, Bone Sialoprotein 1, Uropontin, Secreted Phosphoprotein 1, 106441-73-0