A growth differentiation factor that is secreted in response to cell stress and in response to MACROPHAGE ACTIVATION. In addition growth differentiation factor 15 demonstrates a diverse array of biological properties including the induction of cartilage formation, the inhibition of hematopoietic progenitor proliferation, and the induction of neuronal migration.

Synonyms: 0, Prostate Differentiation Factor, Macrophage Inhibitory Cytokine 1, Growth Differentiation Factor 15, Differentiation Factor, Prostate, GDF-15