An inhibitory B7 antigen that contains V-type and C2 type immunoglobulin domains. It has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN and provides negative signals that control and inhibit T-cell responses. It is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION.

Synonyms: Antigen, B7-H1, Programmed Death Ligand 1, Programmed Cell Death 1 Ligand 1 Protein, PD-L1 Costimulatory Protein, PD L1 Costimulatory Protein, B7 H1 Immune Costimulatory Protein, B7-H1 Antigen, PD L1 Protein, CD274 Antigen, Costimulatory Protein, PD-L1, PD-L1 Protein, Programmed Cell Death 1 Ligand 1, B7 H1 Antigen, 0, B7H1 Immune Costimulatory Protein, Antigens, CD274, CD274 Antigens, B7-H1 Immune Costimulatory Protein, Antigen, CD274

Instance information

comment

2018 (2007) ,2018; see ANTIGENS, CD274 2012-2017

identifier

D060890