Together with the Apc11 subunit, forms the catalytic core of the E3 ubiquitin ligase anaphase-promoting complex (APC-C). Its N-terminus has cullin domains which associate with the RING FINGER DOMAINS of Apc11. Apc2 also interacts with the E2 ubiquitin ligases involved in APC-C ubiquitination reactions.

Synonyms: EC 2.3.2.27, Apc2 Subunit, Anaphase-Promoting Complex-Cyclosome, Apc2 Subunit, Anaphase Promoting Complex, Apc2 Subunit, Anaphase-Promoting Complex, Apc2 Subunit, Anaphase Promoting Complex Cyclosome, Anapc2