An autocrine growth factor and mitogen for a broad range of target cells including EPITHELIAL CELLS; FIBROBLASTS and immune cells. It occurs as a membrane-bound protein that can be cleaved to release an active secreted form.
Synonyms: 0, Schwannoma-derived Growth Factor, Schwannoma derived Growth Factor, Amphiregulin
Instance information
comment
2015 ,2015; AMPHIREGULIN was indexed under INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS 1988-2014
identifier
D066258