|
Amrinone
|
D000676 |
[A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
] |
|
Amsacrine
|
D000677 |
[An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
] |
|
Amsinckia
|
D029682 |
[A plant genus of the family BORAGINACEAE. Members contain PYRROLIZIDINE ALKALOIDS. The common name of burweed is also used for Triumfetta (TILIACEAE).
] |
|
Amsonia
|
D030006 |
[A plant genus of the family APOCYNACEAE. Species of this genus contain YOHIMBINE.
] |
|
Amycolatopsis
|
D000082502 |
[A genus of high GC content gram positive bacteria of the family Pseudonocardiaceae in the order Pseudonocardiales. It is known for producing the antibiotics epoxyquinomycin, VANCOMYCIN, and RISTOCETIN which are used in treating various infections.
] |
|
Amygdala
|
D000679 |
[Almond-shaped group of basal nuclei anterior to the INFERIOR HORN OF THE LATERAL VENTRICLE of the TEMPORAL LOBE. The amygdala is part of the limbic system.
] |
|
Amygdalin
|
D000678 |
[A cyanogenic glycoside found in the seeds of Rosaceae.
] |
|
Amyl Nitrite
|
D000680 |
[A vasodilator that is administered by inhalation. It is also used recreationally due to its supposed ability to induce euphoria and act as an aphrodisiac.
] |
|
Amylases
|
D000681 |
[A group of amylolytic enzymes that cleave starch, glycogen, and related alpha-1,4-glucans. (Stedman, 25th ed) EC 3.2.1.-.
] |
|
Amylin Receptor Agonists
|
D065091 |
[Compounds that stimulate the activity of AMYMIN RECEPTORS. Included under this heading is the endogenous form of ISLET AMYLOID POLYPEPTIDE and synthetic compounds that mimic its effect.
] |
|
Amyloid
|
D000682 |
[A fibrous protein complex that consists of proteins folded into a specific cross beta-pleated sheet structure. This fibrillar structure has been found as an alternative folding pattern for a variety of functional proteins. Deposits of amyloid in the form of AMYLOID PLAQUES are associated with a variety of degenerative diseases. The amyloid structure has also been found in a number of functional proteins that are unrelated to disease.
] |
|
Amyloid Neuropathies
|
D017772 |
[Disorders of the peripheral nervous system associated with the deposition of AMYLOID in nerve tissue. Familial, primary (nonfamilial), and secondary forms have been described. Some familial subtypes demonstrate an autosomal dominant pattern of inheritance. Clinical manifestations include sensory loss, mild weakness, autonomic dysfunction, and CARPAL TUNNEL SYNDROME. (Adams et al., Principles of Neurology, 6th ed, p1349)
] |
|
Amyloid Neuropathies, Familial
|
D028227 |
[Inherited disorders of the peripheral nervous system associated with the deposition of AMYLOID in nerve tissue. The different clinical types based on symptoms correspond to the presence of a variety of mutations in several different proteins including transthyretin (PREALBUMIN); APOLIPOPROTEIN A-I; and GELSOLIN.
] |
|
Amyloid Precursor Protein Secretases
|
D053829 |
[Endopeptidases that are specific for AMYLOID PROTEIN PRECURSOR. Three secretase subtypes referred to as alpha, beta, and gamma have been identified based upon the region of amyloid protein precursor they cleave.
] |
|
Amyloid beta-Peptides
|
D016229 |
[Peptides generated from AMYLOID BETA-PEPTIDES PRECURSOR. An amyloid fibrillar form of these peptides is the major component of amyloid plaques found in individuals with Alzheimer's disease and in aged individuals with trisomy 21 (DOWN SYNDROME). The peptide is found predominantly in the nervous system, but there have been reports of its presence in non-neural tissue.
] |
|
Amyloid beta-Protein Precursor
|
D016564 |
[A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide, AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE PLAQUES.
] |
|
Amyloidogenic Proteins
|
D058227 |
[Proteins that form the core of amyloid fibrils. For example, the core of amyloid A is formed from amyloid A protein, also known as serum amyloid A protein or SAA protein.
] |
|
Amyloidosis
|
D000686 |
[A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.
] |
|
Amyloidosis, Familial
|
D028226 |
[Diseases in which there is a familial pattern of AMYLOIDOSIS.
] |
|
Amylopectin
|
D000687 |
[A highly branched glucan in starch.
] |
