A glycosphingolipid that accumulates due to a deficiency of hexosaminidase A or B (BETA-N-ACETYLHEXOSAMINIDASES), or GM2 activator protein, resulting in GANGLIOSIDOSES, heredity metabolic disorders that include TAY-SACHS DISEASE and SANDHOFF DISEASE.

Synonyms: Ganglioside, GM2 Tay-Sachs Disease Ganglioside G(M2) Ganglioside Ganglioside, Tay-Sachs Disease GM2, Ganglioside Tay Sachs Disease Ganglioside Ganglioside GM2 19600-01-2 GM2 Ganglioside