Integrin alpha4beta1 is a FIBRONECTIN and VCAM-1 receptor present on LYMPHOCYTES; MONOCYTES; EOSINOPHILS; NK CELLS and thymocytes. It is involved in both cell-cell and cell- EXTRACELLULAR MATRIX adhesion and plays a role in INFLAMMATION, hematopoietic cell homing and immune function, and has been implicated in skeletal MYOGENESIS; NEURAL CREST migration and proliferation, lymphocyte maturation and morphogenesis of the PLACENTA and HEART.

Synonyms: Heterodimer alpha4beta1, Integrin Very Late Antigen 4 alpha4beta1, Integrin Heterodimer Integrin alpha(4)beta(1) Integrin Heterodimer alpha4beta1 Integrin alpha4beta1 Integrin, alpha4beta1 alpha4beta1 Integrin VLA-4 Very Late Activation Antigen-4 0 CD49d-CD29 Very Late Antigen-4 Late Antigen-4, Very alpha4beta1, Integrin Very Late Activation Antigen 4 Antigen-4, Very Late