A pre-BCR-negative large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-negative, composed of surrogate light chain protein (SL), which is composed of VpreB and Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu), on the cell surface, and lack a DNA rearrangement of immunoglobulin light chain genes. [ http://purl.obolibrary.org/obo/go/references/0000031 GOC:tfm GOC:rhs http://www.ncbi.nlm.nih.gov/pubmed/9785673 ]
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- large pre-B-II cell and has_not_completed some immunoglobulin light chain V-J recombination and lacks_plasma_membrane_part some pre-B cell receptor complex and lacks_plasma_membrane_part some immunoglobulin iota chain and lacks_plasma_membrane_part some immunoglobulin lambda-like polypeptide 1