A follicular B cell that is IgD-positive, CD23-negative, and CD38-negative. This naive cell type is activated in the extrafollicular areas through interaction with interdigitating dendritic cells and antigen-specific CD4-positive T cells. [ http://www.ncbi.nlm.nih.gov/pubmed/8006591 GOC:dsd http://www.ncbi.nlm.nih.gov/pubmed/18432934 http://www.ncbi.nlm.nih.gov/pubmed/17992590 GOC:msz http://purl.obolibrary.org/obo/go/references/0000031 ]
Synonyms: Bm1 B lymphocyte Bm1 B-cell Bm1 B-lymphocyte
Term information
These cells are also reportedly CD10-negative, CD39-positive, CD44-positive, CD71-negative, CD77-negative, IgM-positive, IgG-negative, IgA-negative, and IgE-negative.
Term relations
- follicular B cell and lacks_plasma_membrane_part some ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 and lacks_plasma_membrane_part some low affinity immunoglobulin epsilon Fc receptor and has plasma membrane part some IgD immunoglobulin complex
- follicular B cell
- fraction F mature B cell
- lacks_plasma_membrane_part some ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
- has plasma membrane part some IgD immunoglobulin complex
- lacks_plasma_membrane_part some low affinity immunoglobulin epsilon Fc receptor