A germinal center B cell that has the phenotype CD77-negative, IgD-negative, and CD38-positive. These cells have undergone somatic mutation of the B cell receptor. [ http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/18432934 GOC:msz GOC:dsd http://www.ncbi.nlm.nih.gov/pubmed/8006591 ]
Synonyms: Bm4 B-lymphocyte Bm4 B lymphocyte Bm4 B-cell
Term information
Bm4 B cells are also reportedly CD10-positive, CD23-negative, CD39-negative, CD44-positive, and CD71-positive.
Term relations
- germinal center B cell and lacks_plasma_membrane_part some IgD immunoglobulin complex and lacks_plasma_membrane_part some lactosylceramide 4-alpha-galactosyltransferase and has plasma membrane part some ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 and output of some somatic hypermutation of immunoglobulin genes
- germinal center B cell
- output of some somatic hypermutation of immunoglobulin genes
- develops from some Bm3-delta B cell
- has plasma membrane part some ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
- lacks_plasma_membrane_part some IgD immunoglobulin complex
- lacks_plasma_membrane_part some lactosylceramide 4-alpha-galactosyltransferase