A memory B cell arising in the germinal center that is IgD-negative and has undergone somatic mutation of the variable region of the immunoglobulin heavy and light chain genes. [ GOC:tfm GOC:dsd http://purl.obolibrary.org/obo/go/references/0000031 GOC:msz http://www.ncbi.nlm.nih.gov/pubmed/18432934 http://www.ncbi.nlm.nih.gov/pubmed/8006591 ]
Synonyms: Bm5 B-cell Bm5 B lymphocyte Bm5 B-lymphocyte
Term information
Bm5 B cells are also reportedly CD10-positive, CD23-negative, CD38-negative, CD39-positive, CD44-positive, CD71-positive, and CD77-negative.
Term relations
- memory B cell and lacks_plasma_membrane_part some IgD immunoglobulin complex and output of some germinal center B cell differentiation and output of some somatic hypermutation of immunoglobulin genes