germinal center B cell differentiation
Go to external page http://purl.obolibrary.org/obo/GO_0002314
The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA). [ GOC:jal https://www.worldcat.org/search?q=bn%3A0781735149 ]
Synonyms: germinal center B-lymphocyte differentiation germinal center B lymphocyte differentiation germinal center B-cell differentiation
Term information
Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Term relations
- cell differentiation
- mature B cell differentiation involved in immune response
- results in acquisition of features of some germinal center B cell