The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation. [ https://www.worldcat.org/search?q=bn%3A081533642X GOC:jal http://purl.obolibrary.org/obo/go/references/0000022 ]
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- anatomical structure formation involved in morphogenesis and results in formation of anatomical entity some secondary nodular lymphoid tissue