A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins. [ http://www.ncbi.nlm.nih.gov/pubmed/7979242 http://www.ncbi.nlm.nih.gov/pubmed/17551517 https://www.worldcat.org/search?q=bn%3A0198506732 http://www.ncbi.nlm.nih.gov/pubmed/17493611 ]