The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies. [ https://www.worldcat.org/search?q=bn%3A0721662544 GOC:dph GOC:mtg_lung ]
Synonyms: great alveolar cell differentiation