A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ. [ http://en.wikipedia.org/wiki/Heart http://orcid.org/0000-0002-6601-2165 ]
Synonyms: vertebrate heart chambered heart
Term information
- BTO:0000562
- MESH:D006321
- ZFA:0000114
- BILA:0000020
- UMLS:C0018787 (ncithesaurus:Heart)
- NCIT:C12727
- EHDAA2:0000738
- galen:Heart
- MAT:0000036
- EFO:0000815
- CALOHA:TS-0445
- MA:0000072
- SCTID:302509004
- EHDAA:420
- Wikipedia:Heart
- XAO:0000064
- VHOG:0000276
- FMA:7088
- AAO:0010210
- EMAPA:16105
- GAID:174
- TAO:0000114
- EV:0100018
- MIAA:0000036
uberon_slim, efo_slim, pheno_slim, vertebrate_core, organ_slim, major_organ, human_reference_atlas
relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO]
Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" DOI:10.1101/gad.1485706
https://cdn.humanatlas.io/digital-objects/ref-organ/heart-male/v1.3/assets/3d-vh-m-heart.glb
https://cdn.humanatlas.io/digital-objects/ref-organ/heart-female/v1.3/assets/3d-vh-f-heart.glb
Blood pumping organ composed of four chambers: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus.[TAO]
Part of the circulatory system responsible for pumping blood; composed of three chambers--two atria and one ventricle.[AAO]
As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[well established][VHOG]
http://purl.obolibrary.org/obo/NCBITaxon_6239
http://purl.obolibrary.org/obo/NCBITaxon_7227
Term relations
- mesoderm-derived structure
- structure with developmental contribution from neural crest
- primary circulatory organ
- thoracic segment organ
- contributes to morphology of some cardiovascular system
- in taxon some Vertebrata
- part of some heart plus pericardium
- in taxon some (not Drosophila melanogaster)
- in taxon some (not Caenorhabditis elegans)
- has developmental contribution from some neural crest
- develops from some heart tube
- has part some cardiac chamber
- heart elastic tissue
- wall of heart
- interventricular foramen of heart
- foramen of Panizza
- cardiac jelly
- mesentery of heart
- bulbar spiral septum
- fibroblast of cardiac tissue
- heart layer
- coronary vessel
- heart blood vessel
- coronary sinus
- atrioventricular nodal artery
- cardiac glial cell
- cardiac endothelial cell
- cardiac blood vessel endothelial cell
- fibrous ring of heart
- bulbo-ventricular groove
- atrioventricular region
- heart endothelium
- basal zone of heart
- coronary artery
- myocardium
- epicardium
- trabecula carnea
- hypobranchial vessel
- mesocardium
- inflow tract
- cardiac mesenchyme
- cardiac valve
- heart vasculature
- coronary capillary
- cardiac skeleton
- cardiac chamber
- outflow tract
- cardiac vein
- bulbus cordis
- endocardium
- apex of heart
- cardiac septum
- endocardial cushion