The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex), the hippocampal formation and the olfactory cortex. [ BIRNLEX:1494 ]
Synonyms: cortex of cerebral hemisphere
Term information
- Wikipedia:Cerebral_cortex
- PBA:128011354
- GAID:629
- BIRNLEX:1494
- NCIT:C12443
- neuronames:39 (BIRNLEX:1494)
- BAMS:C
- EFO:0000328
- MIAA:0000108
- CALOHA:TS-0091
- EV:0100166
- MAT:0000108
- UMLS:C0007776 (ncithesaurus:Cortex)
- EMAPA:17544
- VHOG:0000722
- MESH:D002540
- BAMS:Cerebral_cortex
- FMA:61830
- SCTID:362880003
- BAMS:CTX
- EHDAA:5464
- DHBA:10159
- BTO:0000233
- MA:0000185
- BM:Tel-Cx
- EHDAA2:0000234
- HBA:4008
- BAMS:Cx
- MBA:688
uberon_slim, efo_slim, pheno_slim, human_reference_atlas
We follow NIFSTD in defining cerebral cortex and including both neocortex and hippocampal formation (DG+hippocampus).
http://upload.wikimedia.org/wikipedia/commons/7/7b/Cerebral_Cortex_location.jpg
http://upload.wikimedia.org/wikipedia/commons/9/9a/Brainmaps-macaque-hippocampus.jpg
The cerebral cortex is a structure within the brain that plays a key role in memory, attention, perceptual awareness, thought, language, and consciousness. It constitutes the outermost layer of the cerebrum. In preserved brains, it has a grey color, hence the name 'grey matter'. Grey matter is formed by neurons and their unmyelinated fibers, whereas the white matter below the grey matter of the cortex is formed predominantly by myelinated axons interconnecting different regions of the central nervous system. The human cerebral cortex is 2-4 mm (0.08-0.16 inches) thick. The surface of the cerebral cortex is folded in large mammals, such that more than two-thirds of the cortical surface is buried in the grooves, called 'sulci. ' The phylogenetically most recent part of the cerebral cortex, the neocortex, also called isocortex, is differentiated into six horizontal layers; the more ancient part of the cerebral cortex, the hippocampus (also called archicortex), has at most three cellular layers, and is divided into subfields. Relative variations in thickness or cell type (among other parameters) allow us to distinguish between different neocortical architectonic fields. The geometry of at least some of these fields seems to be related to the anatomy of the cortical folds, and, for example, layers in the upper part of the cortical ridges seem to be more clearly differentiated than in its deeper parts. [WP,unvetted][Wikipedia:Cerebral_cortex].
cortical plate (CTXpl)
brain cortex
pallium of the brain
cortical plate (areas)
cortex cerebri
cortex cerebralis
Migration of neurons from the basal or striatal portions of the anterior part of the neural tube occurs to varying degrees in different vertebrate classes, but a true cerebral cortex is generally acknowledged to have made its first appearance in reptiles. The definition can be unambiguous, since 'cortex' simply implies the existence of a surface neuronal layer with an overlying 'zonal lamina' or 'molecular' layer containing dendrites and axons, which is separated from the underlying basal 'matrix' by white matter. Although reptilian cerebral cortex does indeed fulfill these conditions in certain locations, the separation from striatal structures is often indistinct, so that it may even be argued that some primitive dipnoans possess a pallium or cortex. Nevertheless, an extensive laminated layer separated by underlying white matter is well represented only in reptiles and mammals.[well established][VHOG]
http://purl.obolibrary.org/obo/NCBITaxon_9606
http://purl.obolibrary.org/obo/NCBITaxon_117569
hagfishes have independently evolved a highly laminated cerebral cortex, comparable in many ways to the cerebral cortex of mammals [http://icb.oxfordjournals.org/content/42/4/743]
Term relations
- central nervous system cell part cluster
- central nervous system gray matter layer
- part of some cerebral hemisphere gray matter
- has developmental contribution from some cortical subplate
- contributes to morphology of some telencephalon
- part of some pallium
- has developmental contribution from some cortical plate
- capable of part of some memory
- auditory cortex
- primary motor cortex
- astrocyte of the cerebral cortex
- cerebral cortex glial cell
- cerebral cortex endothelial cell
- Brodmann (1909) area 3
- Brodmann (1909) area 1
- perirhinal cortex
- temporoparietal junction
- paracentral lobule
- neocortex
- perirhinal cortex of rodent of Burwell et al 1995
- koniocortex
- Brodmann area
- cerebral cortex neuropil
- hippocampal formation
- prepyriform area
- calcarine sulcus
- periamygdaloid cortex
- rhinal sulcus
- supplemental motor cortex
- premotor cortex
- insula
- occipital lobe
- Brodmann (1909) area 44
- Brodmann (1909) area 39
- Brodmann (1909) area 46
- Brodmann (1909) area 45
- Brodmann (1909) area 48
- Brodmann (1909) area 47
- Brodmann (1909) area 52
- Brodmann (1909) area 37
- Brodmann (1909) area 34
- Brodmann (1909) area 38
- Brodmann (1909) area 6
- Brodmann (1909) area 5
- Brodmann (1909) area 30
- Brodmann (1909) area 18
- prefrontal cortex
- central sulcus
- layer of developing cerebral cortex
- secondary olfactory cortex
- olfactory cortex
- gyrus
- lateral sulcus
- periallocortex
- paleocortex
- allocortex
- visceral area
- dorsal peduncular area
- piriform-amygdalar area
- cortical visual area
- gustatory cortex
- paracingulate gyrus
- dorsolateral prefrontal cortex
- Brodmann (1909) area 31