The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. [ https://sourceforge.net/p/geneontology/ontology-requests/11422/ http://amigo.geneontology.org/amigo/term/GO:0021551 http://www.frontiersinzoology.com/content/7/1/29 ]
Synonyms: systema nervosum centrale CNS
Term information
- ZFA:0000012
- BIRNLEX:1099
- Wikipedia:Central_nervous_system
- BILA:0000080
- NCIT:C12438
- TAO:0000012
- BAMS:CNS
- EHDAA:828
- VHOG:0000293
- FBbt:00005094 (ManualMappingCuration)
- UMLS:C0927232 (ncithesaurus:Central_Nervous_System)
- EHDAA2:0000225
- MESH:D002490
- CALOHA:TS-0150
- neuronames:854
- MAT:0000457
- FMA:55675
- MA:0000167
- GAID:570
- EFO:0000908
- SCTID:278199004
- AAO:0000090
- EMAPA:16754
- EV:0100163
- XAO:0000215
- BTO:0000227
- EMAPA:16470
cumbo, uberon_slim, efo_slim, pheno_slim, vertebrate_core, human_reference_atlas
The brain and spinal cord. Kimmel et al, 1995.[TAO]
The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO).
Part of the nervous system which includes the brain and spinal cord.[AAO]
(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2); Taken together, our data make a very strong case that the complex molecular mediolateral architecture of the developing trunk CNS (central nervous system), as shared between Platynereis and vertebrates, was already present in their last common ancestor, Urbilateria. The concept of bilaterian nervous system centralization implies that neuron types concentrate on one side of the trunk, as is the case in vertebrates and many invertebrates including Platynereis, where they segregate and become spatially organized (as opposed to a diffuse nerve net). Our data reveal that a large part of the spatial organization of the annelid and vertebrate CNS was already present in their last common ancestor, which implies that Urbilateria had already possessed a CNS (reference 3).[well established][VHOG]
Term relations
- organ system subdivision
- ectoderm-derived structure
- immediate transformation of some future central nervous system
- part of some nervous system
- in taxon some (not Acoelomorpha)
- develops from some future central nervous system
- in taxon some Bilateria
- axon tract
- central nervous system pericyte
- ganglion of central nervous system
- oligodendrocyte precursor cell
- oligodendrocyte
- CNS neuron (sensu Vertebrata)
- central nervous system macrophage
- parenchyma of central nervous system
- hindbrain-spinal cord boundary
- ventricular system of central nervous system
- future spinal cord
- central nervous system cell part cluster
- Reissner's fiber
- infundibular organ
- vasculature of central nervous system
- neural nucleus
- rubroreticular tract
- medial corticohypothalmic tract
- cranial nerve II
- circuit part of central nervous system
- brain
- pineal tract
- epiphyseal tract
- meningeal cluster
- root of cranial nerve
- insect stomatogastric nervous system
- spinal cord
- gray matter
- neuropil
- lumen of central nervous system
- white matter