JSON

spleen

Go to external page http://purl.obolibrary.org/obo/UBERON_0002106

The organ that functions to filter blood and to store red corpuscles and platelets. [ MP:0000689 https://www.worldcat.org/search?q=bn%3A0-683-40008-8 ]

This is just here as a test because I lose it

Term information

database cross reference
  • EV:0100055
  • CALOHA:TS-0956
  • FMA:7196
  • MIAA:0000085
  • EFO:0000869
  • galen:Spleen
  • GAID:1289
  • AAO:0010395
  • SCTID:181279003
  • TAO:0000436
  • XAO:0000328
  • MAT:0000085
  • UMLS:C0037993 (ncithesaurus:Spleen)
  • VHOG:0000120
  • Wikipedia:Spleen
  • EMAPA:18767
  • BTO:0001281
  • NCIT:C12432
  • MESH:D013154
  • ZFA:0000436
  • MA:0000141
Subsets

uberon_slim, efo_slim, pheno_slim, vertebrate_core, organ_slim, human_reference_atlas

depiction

https://cdn.humanatlas.io/digital-objects/ref-organ/spleen-female/v1.3/assets/3d-vh-f-spleen.glb

https://upload.wikimedia.org/wikipedia/commons/d/d6/Illu_spleen.jpg

https://cdn.humanatlas.io/digital-objects/ref-organ/spleen-male/v1.3/assets/3d-vh-m-spleen.glb

external definition

An organ involved in red blood cell filtration and immune response.[AAO]

function notes

It synthesizes antibodies in its white pulp and removes, from blood and lymph node circulation, antibody-coated bacteria along with antibody-coated blood cells

has relational adjective

lienal

splenic

homology notes

With the advent of clonal selection, the accumulation and segregation of T and B cells in specialized organs for antigen presentation became necessary, and indeed the spleen is found in all jawed vertebrates, but not in agnathans or invertebrates.[well established][VHOG]

id

UBERON:0002106

present in taxon

http://purl.obolibrary.org/obo/NCBITaxon_9606

taxon notes

In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve in case of hemorrhagic shock, especially in animals like horses (not in humans), while recycling iron

Neither hagfish nor lampreys possess what might be considered a discrete and condensed spleen. Hagfish possess dispersed lymphoid tissue within the submucosa of the intestine (96) associated with the portal vein (97), whereas lymphoid tissue is associated with the typhlosole portion of the intestine in lampreys (96)