The region of the hepatic acinus immediately surrounding the central veins. This region has the lowest oxygen concentration in the acinus. Zone 3 is located in the centrilobular region of the liver lobule, closest to the central vein. Hepatocytes in this region are the primary location for the biotransformation of drugs. [ http://www.ncbi.nlm.nih.gov/pubmed/29763190 ]
Synonyms: hepatic acinus pericentral zone hepatic acinus centrilobular zone hepatic acinus perivenous zone