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preBCR-positive large pre-B-II cell
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CL_0000952 |
[An preBRC-positive large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-positive, composed of surrogate light chain protein (SL), which is composed of VpreB , Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu) on the cell surface.] |
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pre-B-I cell
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CL_0000956 |
[A pre-B-I cell is a precursor B cell that expresses CD34 and surrogate immunoglobulin light chain (VpreB , Lambda 5 (mouse)/14.1 (human)) on the cell surface, and TdT, Rag1,and Rag2 intracellularly. Cell type carries a D-JH DNA rearrangement, and lacks expression of immunglobulin heavy chain protein.] |
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Bm2 B cell
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CL_0000962 |
[A follicular B cell that is IgD-positive and CD23-positive and CD38-positive. This naive cell type is activated in the extrafollicular areas via interaction with dendritic cells and antigen specific T cells.] |
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follicular B cell
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CL_0000843 |
[A resting mature B cell that has the phenotype IgM-positive, IgD-positive, CD23-positive and CD21-positive, and found in the B cell follicles of the white pulp of the spleen or the corticol areas of the peripheral lymph nodes. This cell type is also described as being CD19-positive, B220-positive, AA4-negative, CD43-negative, and CD5-negative.] |
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Bm1 B cell
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CL_0000961 |
[A follicular B cell that is IgD-positive, CD23-negative, and CD38-negative. This naive cell type is activated in the extrafollicular areas through interaction with interdigitating dendritic cells and antigen-specific CD4-positive T cells.] |
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fraction F mature B cell
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CL_0002056 |
[A mature B cell subset originally defined as having being CD45R-positive, IgM-positive, IgD-positive and CD43-negative. Subsequent research demonstrated being CD21-positive and CD23-negative and CD93 negative.] |
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Bm4 B cell
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CL_0000966 |
[A germinal center B cell that has the phenotype CD77-negative, IgD-negative, and CD38-positive. These cells have undergone somatic mutation of the B cell receptor.] |
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germinal center B cell
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CL_0000844 |
[A rapidly cycling mature B cell that has distinct phenotypic characteristics and is involved in T-dependent immune responses and located typically in the germinal centers of lymph nodes. This cell type expresses Ly77 after activation.] |
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Bm3 B cell
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CL_0000965 |
[A germinal center B cell that is rapidly dividing and has the phenotype IgD-negative, CD38-positive, and CD77-positive. Somatic hypermutation of the immunoglobulin V gene region can occur during proliferation of this cell type.] |
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Bm2' B cell
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CL_0000964 |
[A germinal center B cell that founds a germinal center, and has the phenotype IgD-positive, CD38-positive, and CD23-negative.] |
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Bm3-delta B cell
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CL_0000963 |
[A germinal center B cell that develops from a Bm3 B cell. This cell has the phenotype IgM-negative, IgD-positive, and CD38-positive.] |
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Bm5 B cell
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CL_0000967 |
[A memory B cell arising in the germinal center that is IgD-negative and has undergone somatic mutation of the variable region of the immunoglobulin heavy and light chain genes.] |
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IgA memory B cell
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CL_0000973 |
[A class switched memory B cell that expresses IgA.] |
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IgM memory B cell
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CL_0000971 |
[An IgM memory B cell is an unswitched memory B cell with the phenotype IgM-positive and IgD-negative.] |
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unswitched memory B cell
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CL_0000970 |
[An unswitched memory B cell is a memory B cell that has the phenotype IgM-positive, IgD-positive, CD27-positive, CD138-negative, IgG-negative, IgE-negative, and IgA-negative.] |
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IgG memory B cell
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CL_0000979 |
[An IgG memory B cell is a class switched memory B cell that is class switched and expresses IgG on the cell surface.] |
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plasmablast
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CL_0000980 |
[An activated mature (naive or memory) B cell that is secreting immunoglobulin, typified by being CD27-positive, CD38-positive, CD138-negative.] |
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mature B cell
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CL_0000785 |
[A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen.] |
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double negative memory B cell
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CL_0000981 |
[A memory B cell with the phenotype IgD-negative and CD27-negative.] |
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Didelphimorphia
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NCBITaxon_38605 |
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